abstract：:A method was developed to quantify the performance of microorganisms involved in different digestion levels in biogas plants. The test system was based on the addition of butyrate (BCON), ethanol (ECON), acetate (ACON) or propionate (PCON) to biogas sludge samples and the subsequent analysis of CH4 formation in compar...

journal_title：Journal of industrial microbiology & biotechnology

authors： Refai S,Berger S,Wassmann K,Hecht M,Dickhaus T,Deppenmeier U

更新日期：2017-03-01 00:00:00

abstract：:Rapamycin, as a macrocyclic polyketide with immunosuppressive, antifungal, and anti-tumor activity produced by Streptomyces hygroscopicus, is receiving considerable attention for its significant contribution in medical field. However, the production capacity of the wild strain is very low. Hereby, a computational guid...

journal_title：Journal of industrial microbiology & biotechnology

authors： Dang L,Liu J,Wang C,Liu H,Wen J

更新日期：2017-02-01 00:00:00

abstract：:The dissolved oxygen (DO) level of a culture of Corynebacterium glutamicum (C. glutamicum) in a bioreactor has a significant impact on the cellular redox potential and the distribution of energy and metabolites. In this study, to gain a deeper understanding of the effects of DO on the metabolism of C. glutamicum, we s...

journal_title：Journal of industrial microbiology & biotechnology

authors： Liu X,Yang S,Wang F,Dai X,Yang Y,Bai Z

更新日期：2017-02-01 00:00:00

abstract：:Nitrogen deprivation (N-deprivation) is a proven strategy for inducing triacylglyceride accumulation in microalgae. However, its effect on the physical properties of cells and subsequently on product recovery processes is relatively unknown. In this study, the effect of N-deprivation on the cell size, cell wall thickn...

journal_title：Journal of industrial microbiology & biotechnology

authors： Yap BH,Crawford SA,Dagastine RR,Scales PJ,Martin GJ

更新日期：2016-12-01 00:00:00

abstract：:Physiological studies and biotechnology applications of Geobacter species have been limited by a lack of genetic tools. Therefore, potential additional molecular strategies for controlling metabolism were explored. When the gene for citrate synthase, or acetyl-CoA transferase, was placed under the control of a LacI/IP...

journal_title：Journal of industrial microbiology & biotechnology

authors： Ueki T,Nevin KP,Woodard TL,Lovley DR

更新日期：2016-11-01 00:00:00

abstract：:A polyene compound NPP identified in Pseudonocardia autotrophica was shown to contain an aglycone identical to nystatin, but to harbor a unique disaccharide moiety that led to higher solubility and reduced hemolytic activity. Recently, it was revealed that the final step of NPP (nystatin-like polyene) biosynthesis is ...

journal_title：Journal of industrial microbiology & biotechnology

authors： Kim MK,Won HJ,Kim HJ,Choi SS,Lee HS,Kim P,Kim ES

更新日期：2016-11-01 00:00:00

abstract：:Crude glycerol obtained as a by-product of biodiesel production is a reliable feedstock with the potential to be converted into reduced chemicals with high yields. It has been previously shown that ethanol is the primary product of glycerol fermentation by Escherichia coli. However, few efforts were made to enhance th...

journal_title：Journal of industrial microbiology & biotechnology

authors： Loaces I,Rodríguez C,Amarelle V,Fabiano E,Noya F

更新日期：2016-10-01 00:00:00

abstract：:Acidophilic microorganisms involved in uranium bioleaching are usually suppressed by dissolved fluoride ions, eventually leading to reduced leaching efficiency. However, little is known about the regulation mechanisms of microbial resistance to fluoride. In this study, the resistance of Acidithiobacillus ferrooxidans ...

journal_title：Journal of industrial microbiology & biotechnology

authors： Ma L,Li Q,Shen L,Feng X,Xiao Y,Tao J,Liang Y,Yin H,Liu X

更新日期：2016-10-01 00:00:00

abstract：:Microbial fermentation of sugars from plant biomass to alcohols represents an alternative to petroleum-based fuels. The optimal biocatalyst for such fermentations needs to overcome hurdles such as high concentrations of alcohols and toxic compounds. Lactic acid bacteria, especially lactobacilli, have high innate alcoh...

journal_title：Journal of industrial microbiology & biotechnology

authors： Vinay-Lara E,Wang S,Bai L,Phrommao E,Broadbent JR,Steele JL

更新日期：2016-09-01 00:00:00

abstract：:In this study, the respiratory activity and carbon usage of the mutant strain of A. vinelandii AT6, impaired in poly-β-hydroxybutyrate (PHB) production, and their relationship with the synthesis of alginate were evaluated. The alginate yield and the specific oxygen uptake rate were higher (2.5-fold and 62 %, respectiv...

journal_title：Journal of industrial microbiology & biotechnology

authors： Jiménez L,Castillo T,Flores C,Segura D,Galindo E,Peña C

更新日期：2016-08-01 00:00:00

abstract：:In this study, we detail the specificity of an aspartic peptidase from Rhizomucor miehei and evaluate the effects of this peptidase on clotting milk using the peptide sequence of k-casein (Abz-LSFMAIQ-EDDnp) and milk powder. Molecular mass of the peptidase was estimated at 37 kDa, and optimum activity was achieved at ...

journal_title：Journal of industrial microbiology & biotechnology

authors： da Silva RR,Souto TB,de Oliveira TB,de Oliveira LC,Karcher D,Juliano MA,Juliano L,de Oliveira AH,Rodrigues A,Rosa JC,Cabral H

更新日期：2016-08-01 00:00:00

abstract：:Ethyl carbamate (EC), a pluripotent carcinogen, is mainly formed by a spontaneous chemical reaction of ethanol with urea in wine. The arginine, one of the major amino acids in grape musts, is metabolized by arginase (encoded by CAR1) to ornithine and urea. To reduce the production of urea and EC, an arginase-deficient...

journal_title：Journal of industrial microbiology & biotechnology

authors： Guo XW,Li YZ,Guo J,Wang Q,Huang SY,Chen YF,Du LP,Xiao DG

更新日期：2016-05-01 00:00:00

abstract：:The objective of this study was to demonstrate the feasibility of novel, Horizontal Flow Biofilm Reactor (HFBR) technology for the treatment of ammonia (NH3)-contaminated airstreams. Three laboratory-scale HFBRs were used for remediation of an NH3-containing airstream at 10 °C during a 90-d trial to test the efficacy ...

journal_title：Journal of industrial microbiology & biotechnology

authors： Gerrity S,Clifford E,Kennelly C,Collins G

更新日期：2016-05-01 00:00:00

abstract：:Nucleoside antibiotics constitute an important family of microbial natural products bearing diverse bioactivities and unusual structural features. Their biosynthetic logics are unique with involvement of complex multi-enzymatic reactions leading to the intricate molecules from simple building blocks. Understanding how...

journal_title：Journal of industrial microbiology & biotechnology

authors： Chen W,Qi J,Wu P,Wan D,Liu J,Feng X,Deng Z

更新日期：2016-03-01 00:00:00

abstract：:Natural products are a crucial source of antimicrobial agents, but reliance on low-resolution bioactivity-guided approaches has led to diminishing interest in discovery programmes. Here, we demonstrate that two in-house automated informatic platforms can be used to target classes of biologically active natural product...

journal_title：Journal of industrial microbiology & biotechnology

authors： Johnston CW,Connaty AD,Skinnider MA,Li Y,Grunwald A,Wyatt MA,Kerr RG,Magarvey NA

更新日期：2016-03-01 00:00:00

abstract：:Actinomycetes continue to be important sources for the discovery of secondary metabolites for applications in human medicine, animal health, and crop protection. With the maturation of actinomycete genome mining as a robust approach to identify new and novel cryptic secondary metabolite gene clusters, it is critical t...

journal_title：Journal of industrial microbiology & biotechnology

authors： Baltz RH

更新日期：2016-03-01 00:00:00

abstract：:Isoamylase catalyzes the hydrolysis of α-1,6-glycosidic linkages in glycogen, amylopectin and α/β-limit dextrins. A semi-rational design strategy was performed to improve catalytic properties of isoamylase from Bacillus lentus. Three residues in vicinity of the essential residues, Arg505, Asn513, and Gly608, were chos...

journal_title：Journal of industrial microbiology & biotechnology

authors： Li Y,Zhang L,Ding Z,Gu Z,Shi G

更新日期：2016-01-01 00:00:00

abstract：:The Saccharomyces cerevisiae HAP4 gene encodes a transcription activator that plays a key role in controlling the expression of genes involved in mitochondrial respiration and reductive pathways. This work examines the effect of knockout of the HAP4 gene on aerobic ethanol production in a xylose-utilizing S. cerevisia...

journal_title：Journal of industrial microbiology & biotechnology

authors： Matsushika A,Hoshino T

更新日期：2015-12-01 00:00:00

abstract：:D-tagatose is produced from D-galactose by the enzyme L-arabinose isomerase (L-AI) in a commercially viable bioprocess. An active and stable biocatalyst was obtained by modifying chitosan gel structure through reaction with TNBS, D-fructose or DMF, among others. This led to a significant improvement in L-AI immobiliza...

journal_title：Journal of industrial microbiology & biotechnology

authors： Manzo RM,de Sousa M,Fenoglio CL,Gonçalves LR,Mammarella EJ

更新日期：2015-10-01 00:00:00

abstract：:L-Phenylalanine ammonia-lyase (PAL, EC 4.3.1.25) from Rhodosporidium toruloides was utilized to remove L-phenylalanine (L-Phe) from different commercial protein hydrolysates. A casein acid hydrolysate (CAH, L-Phe ~2.28 %) was employed as a model substrate. t-Cinnamic acid resulting from deamination of L-Phe was extrac...

journal_title：Journal of industrial microbiology & biotechnology

authors： Castañeda MT,Adachi O,Hours RA

更新日期：2015-10-01 00:00:00

abstract：:The phytase of the yeast Pichia anomala (PPHY) is a suitable biocatalyst as a food and feed additive because of its adequate thermostability, acid stability, protease insensitivity and broad substrate spectrum. The cell-bound nature and low phytase titres are the main bottlenecks for its utility in food and feed indus...

journal_title：Journal of industrial microbiology & biotechnology

authors： Joshi S,Satyanarayana T

更新日期：2015-10-01 00:00:00

abstract：:The application of sub-lethal stresses is known to be an efficient strategy to enhance survival of probiotic bacteria during drying processes. In this context, we previously showed that the application of heat stress upon the entry into stationary phase increased significantly the viability of Bifidobacterium bifidum....

journal_title：Journal of industrial microbiology & biotechnology

authors： Nguyen HT,Razafindralambo H,Richel A,Jacquet N,Evrard P,Antoine P,Thonart P,Delvigne F

更新日期：2015-09-01 00:00:00

abstract：:Anaerobic digestion is a sustainable technology for the treatment of organic waste and production of biogas. Acetoclastic methanogenesis accounts for the majority of methane production in anaerobic digestion. Therefore, sustaining robust acetoclastic methanogens is important for stable process performance. Due to fast...

journal_title：Journal of industrial microbiology & biotechnology

authors： Chen S,He Q

更新日期：2015-08-01 00:00:00

abstract：:A novel chromatic visible screening method using bromothymol blue (BTB) as a color indicator and cetylpyridinium chloride (CPC) as a mediator was constructed to obtain the high titer surfactin-producing strains. The reliability and quantification accuracy of color shift were also confirmed. Regular chromatic responses...

journal_title：Journal of industrial microbiology & biotechnology

authors： Yang H,Yu H,Shen Z

更新日期：2015-08-01 00:00:00

abstract：:A closed-circuit microbial fuel cell (C-MFC) was operated to investigate the electron flux under fed-batch mode, and the results were compared to those of open-circuit MFC (O-MFC) and a fermentation reactor (F-reactor). The current was the largest electron sink (52.7% of influent SCOD) in C-MFC, whereas biomass and me...

journal_title：Journal of industrial microbiology & biotechnology

authors： Yu J,Park Y,Lee T

更新日期：2015-07-01 00:00:00

abstract：:A medium-chain-length poly-3-hydroxyalkanote (MCL-PHA) depolymerase knockout mutant of Pseudomonas putida KT2440 was produced by double homologous recombination. A carbon-limited shake-flask study confirmed that depolymerase activity was eliminated. Lysis of both mutant and wild-type strains occurred under these condi...

journal_title：Journal of industrial microbiology & biotechnology

authors： Vo MT,Ko K,Ramsay B

更新日期：2015-04-01 00:00:00

abstract：:Given the recent increases in natural gas reserves and associated drawbacks of current gas-to-liquids technologies, the development of a bioconversion process to directly convert methane to liquid fuels would generate considerable industrial interest. Several clades of anaerobic methanotrophic archaea (ANME) are capab...

journal_title：Journal of industrial microbiology & biotechnology

authors： Mueller TJ,Grisewood MJ,Nazem-Bokaee H,Gopalakrishnan S,Ferry JG,Wood TK,Maranas CD

更新日期：2015-03-01 00:00:00

abstract：:Bioethanol fermentations expose yeasts to a new, complex and challenging fermentation medium with specific inhibitors and sugar mixtures depending on the type of carbon source. It is, therefore, suggested that the natural diversity of yeasts should be further exploited in order to find yeasts with good ethanol yield i...

journal_title：Journal of industrial microbiology & biotechnology

authors： Ruyters S,Mukherjee V,Verstrepen KJ,Thevelein JM,Willems KA,Lievens B

更新日期：2015-01-01 00:00:00

abstract：:Marine sediments from Newfoundland, Canada were explored for biotechnologically promising Actinobacteria using culture-independent and culture-dependent approaches. Culture-independent pyrosequencing analyses uncovered significant actinobacterial diversity (H'-2.45 to 3.76), although the taxonomic diversity of biotech...

journal_title：Journal of industrial microbiology & biotechnology

authors： Duncan KR,Haltli B,Gill KA,Correa H,Berrué F,Kerr RG

更新日期：2015-01-01 00:00:00

abstract：:Component C (Acarviosy-1,4-Glc-1,1-Glc) was a highly structural acarbose analog, which could be largely formed during acarbose fermentation process, resulting in acarbose purification being highly difficult. By choosing osmolality level as the key fermentation parameter of acarbose-producing Actinoplanes sp. A56, this...

journal_title：Journal of industrial microbiology & biotechnology

authors： Cheng X,Peng WF,Huang L,Zhang B,Li KT

更新日期：2014-12-01 00:00:00

abstract：:Our previous work revealed proanthocyanidins (PAs) could pose significant enhancement on the activity of H(+)-ATPase and fermentation efficiency after a transient initial inhibition (Li et al in Am J Enol Vitic 62(4):512-518, 2011). The aim of the present work was to understand the possible mechanism for this regulati...

journal_title：Journal of industrial microbiology & biotechnology

authors： Li J,Zhao H,Huang W

更新日期：2014-12-01 00:00:00

abstract：:Human-like collagen (HLC) is a novel biomedical material with promising applications. Usually, insoluble HLC was formed due to over-expression. In order to improve the production of soluble HLC, the effective chaperone proteins and their mediation roles on HLC were clarified. Trigger factor (TF) pathway with low speci...

journal_title：Journal of industrial microbiology & biotechnology

authors： Jia Q,Luo Y

更新日期：2014-11-01 00:00:00

abstract：:Genistin and daidzein exhibit a protective effect on DNA damage and inhibit cell proliferation. Glycosylation and malonylation of the compounds increase water solubility and stability. Constructed pET15b-GmIF7GT and pET28a-GmIF7MAT were used for the transformation of Escherichia coli and bioconversion of genistein and...

journal_title：Journal of industrial microbiology & biotechnology

authors： Koirala N,Pandey RP,Thang DV,Jung HJ,Sohng JK

更新日期：2014-11-01 00:00:00

abstract：:Liquid phase oxidation process using chelated iron solution is among the most promising techniques for the hydrogen sulfide removal due to its double advantage of waste minimization and resource recovery. Regeneration of chelated iron is a core reaction in this process. Regeneration of chelated iron in acidic solution...

journal_title：Journal of industrial microbiology & biotechnology

authors： Wang YJ,Li DP,Liu C,Zhan GQ,He XH

更新日期：2014-11-01 00:00:00

abstract：:As one of the major microbes in the soy sauce fermentation, Candida versatilis enriches the flavor and improves the quality of soy sauce. In this study, a combination of five different GC-MS and LC-MS-based metabolome analytical approaches was used to analyze the intracellular, extracellular and whole metabolites of C...

journal_title：Journal of industrial microbiology & biotechnology

authors： Qi W,Fan ZC,Wang CL,Hou LH,Liu JF,Cao XH

更新日期：2014-10-01 00:00:00

abstract：:Production of recombinant proteins is an industrially important technique in the biopharmaceutical sector. Many recombinant proteins are problematic to generate in a soluble form in bacteria as they readily form insoluble inclusion bodies. Recombinant protein solubility can be enhanced by minimising stress imposed on ...

journal_title：Journal of industrial microbiology & biotechnology

authors： Wyre C,Overton TW

更新日期：2014-09-01 00:00:00

abstract：:To improve the thermostability of a mesophilic GH family 10 xylanase, AuXyn10A, from Aspergillus usamii E001, its modification was performed by in silico design. Based on the comparison of B-factor values, a mutant xylanase ATXyn10 was predicted by substituting a segment YP from Tyr(25) to Pro(34) of AuXyn10A with the...

journal_title：Journal of industrial microbiology & biotechnology

authors： Wang J,Tan Z,Wu M,Li J,Wu J

更新日期：2014-08-01 00:00:00

abstract：:Production of recombinant protein bio-insecticides on a commercial scale can only be cost effective if host strains with very high expression levels are available. A recombinant fusion protein containing an arthropod toxin, ω-hexatoxin-Hv1a, (from funnel web spider Hadronyche versuta) linked to snowdrop lectin (Galant...

journal_title：Journal of industrial microbiology & biotechnology

authors： Pyati P,Fitches E,Gatehouse JA

更新日期：2014-08-01 00:00:00

abstract：:Huperzine A (HupA), a naturally occurring lycopodium alkaloid, is a potent, highly specific and reversible inhibitor of acetylcholinesterase and is a potential treatment for Alzheimer's disease. However, isolating HupA from Huperziaceae plants is inefficient; thus, extracting this compound from endophytic fungi may be...

journal_title：Journal of industrial microbiology & biotechnology

authors： Yan R,Zhang Z,Wang Y,Yang H,Zeng Q,Zhu D

更新日期：2014-07-01 00:00:00

abstract：:Three identical lab-scale biocovers were packed with an engineered soil (BC 1), tobermolite only (BC 2), and a mixture of the soil and tobermolite (BC 3), and were operated at an inlet load of 338-400 g-CH4 m(-2) d(-1) and a space velocity of 0.12 h(-1). The methane removal capacity was 293 ± 47 g-CH4 m(-2) d(-1) in s...

journal_title：Journal of industrial microbiology & biotechnology

authors： Moon KE,Lee EH,Kim TG,Cho KS

更新日期：2014-07-01 00:00:00